90plus 纳米粒度仪应用案例-6

文献名:aluminananoparticlesinduceexpressionofendothelialcelladhesionmolecules
作者:elizabethoesterlinga,nitinchoprab,vasileiosgavalasb,xabierarzuagac,eunjinlimc,
rukhsanasultanab,d.allanbutterfieldb,leonidasbachasb,bernhardhenniga,c
agraduatecenterfortoxicology,universityofkentucky,lexington,ky40536,unitedstates
bdepartmentofchemistryandcenterofmembranesciences,universityofkentucky,lexington,ky40536,unitedstates
cmolecularandcellnutritionlaboratory,collegeofagriculture,universityofkentucky,lexington,ky40536-0200,unitedstates
摘要:nanotechnologyisarapidlygrowingindustrythathaselicitedmuchconcernbecauseofthelackofavailabletoxicitydata.exposuretoultrafineparticlesmaybeariskforthedevelopmentofvasculardiseasesduetodysfunctionofthevascularendothelium.increasedendothelialadhesivenessisacriticalfirststepinthedevelopmentofvasculardiseases,suchasatherosclerosis.thehypothesisthataluminananoparticlesincreaseinflammatorymarkersoftheendothelium,measuredbytheinductionofadhesionmoleculesaswellastheadhesionofmonocytestotheendothelialmonolayer,wastested.followingcharacterizationofaluminananoparticlesbytransmissionelectronmicroscopy(tem),electrondiffraction,andparticlesizedistributionanalysis,endothelialcellswereexposedtoaluminaatvariousconcentrationsandtimes.bothporcinepulmonaryarteryendothelialcellsandhumanumbilicalveinendothelialcellsshowedincreasedmrnaandproteinexpressionofvcam-1,icam-1,andelam-1.furthermore,humanendothelialcellstreatedwithaluminaparticlesshowedincreasedadhesionofactivatedmonocytes.thealuminaparticlestendedtoagglomerateatphysiologicalphinserum-containingmedia,whichledtoarangeofparticlesizesfromnanotomicronsizeduringtreatmentconditions.thesedatashowthataluminananoparticlescanelicitaproinflammatoryresponseandthuspresentacardiovasculardiseaserisk.

影响比色计测量结果的因素汇总
沥青混合料动态疲劳试验机应用范围
恒温恒湿试验箱箱出现频繁跳闸的情况应如何处理?
立式多级离心泵汽蚀余量的解决?
热转印机的操作和特点
90plus 纳米粒度仪应用案例-6
如何排除叉车制定系统中的空气
箱式电阻炉是干什么用的?
微晶纳米新型电热套技术优势
自动双管馏程测定仪YSZ-II
信百诺饰面人造板甲醛释放仓介绍
电磁兼容测试项目表sz3ctest
高压涡轮风机运转时使用要点
超微量分光光度计对工作环境的要求有哪些?
FESTO电磁阀结合了众多优点开发而成
圆弧齿轮泵概述
祁县阻燃防火包带一卷多少米
能够持续试验的恒温制冷式微机全自动建材制品燃烧热值试验装置
FAQ:DR/2000内存出错W
德国IFM压力传感器现货总经销