11β-HSD2 抗体说明书
rabbitanti-11β-hsd2 抗体说明书
from:abcam
catalog number :hz982114
quantity size : 0.2ml（dilute with ph 7.4 0.01 m pbs or antibody diluent ）
background:glucocorticoid hormone action in target tissues is modulated by 11β-hydroxysteroid dehydrogenase （11β-hsd）, which catalyzes the interconversion of hormonally active c11-hydroxylated corticosteroids （cortisol, corticosterone） and their inactive c11-keto metabolites （cortisone, 11-dehydrocorticosterone）. at least two isoforms of 11β-hsd exist a low-affinity nadp-dependent dehydrogenase/oxoreductase （11β-hsd2） and a high-affinity nad-dependent dehydrogenase （11β-hsd2）. the glycosylated 11β-hsd2 protein activates cortisol from cortisone, which is widely expressed in mammals, and is most highly expressed in the liver . 11β-hsd2 inactivates cortisol to cortisone and is expressed in placenta, aldosterone target tissues （kidney, parotid, colon and skin） and pancreas. 11β-hsd2 may play a role in glucose homeostasis and pathogenesis of a number of disorders including insulin resistance and obesity. 11β-hsd2 associates with differentiation or maturation in human colonic epithelia and may serve as a marker in development and disease. in addition, 11β-hsd2 plays a crucial role in modulating mineralcorticoid and glucocorticoid receptor occupancy by glucocorticoids.
11β-hsd2 抗体说明书pecificity :
– anti- 11β-hsd2 is a rabbit monoclonal antibody unconjugated
– specific for 11β-hsd2 of human, mouse, rat
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– protein g affinity chromatography purification, purity :>95%
– isotype: igg
– mol wt: 34kda
application :
– western blotting 1:100-500
– immunohistochemistry 1:100-500
– elisa 1:500-1000
– optimal working dilutions mustbe determined by the end user.
storage:store at -20℃ for one year. avoid repeated freeze/thaw cycles. thelyophilized antibody is stable at room temperature for at least one month and for greaterthan a year when kept at -20℃. when reconstituted in sterile ph 7.4 0.01m pbs or diluentof antibody, the antibody is stable for at least six weeks at 2-4 ℃
important note: this product as supplied is intended for research use only, not for use inhuman, therapeutic or diagnostic applications.
11β-hsd2 抗体说明书
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from:abcam
catalog number :hz982114
quantity size : 0.2ml（dilute with ph 7.4 0.01 m pbs or antibody diluent ）
background:glucocorticoid hormone action in target tissues is modulated by 11β-hydroxysteroid dehydrogenase （11β-hsd）, which catalyzes the interconversion of hormonally active c11-hydroxylated corticosteroids （cortisol, corticosterone） and their inactive c11-keto metabolites （cortisone, 11-dehydrocorticosterone）. at least two isoforms of 11β-hsd exist a low-affinity nadp-dependent dehydrogenase/oxoreductase （11β-hsd2） and a high-affinity nad-dependent dehydrogenase （11β-hsd2）. the glycosylated 11β-hsd2 protein activates cortisol from cortisone, which is widely expressed in mammals, and is most highly expressed in the liver . 11β-hsd2 inactivates cortisol to cortisone and is expressed in placenta, aldosterone target tissues （kidney, parotid, colon and skin） and pancreas. 11β-hsd2 may play a role in glucose homeostasis and pathogenesis of a number of disorders including insulin resistance and obesity. 11β-hsd2 associates with differentiation or maturation in human colonic epithelia and may serve as a marker in development and disease. in addition, 11β-hsd2 plays a crucial role in modulating mineralcorticoid and glucocorticoid receptor occupancy by glucocorticoids.
11β-hsd2 抗体说明书pecificity :
– anti- 11β-hsd2 is a rabbit monoclonal antibody unconjugated
– specific for 11β-hsd2 of human, mouse, rat
– use for western blotting,elisa,immunoprecipitation and immunohistochemistry
– protein g affinity chromatography purification, purity :>95%
– isotype: igg
– mol wt: 34kda
application :
– western blotting 1:100-500
– immunohistochemistry 1:100-500
– elisa 1:500-1000
– optimal working dilutions mustbe determined by the end user.
storage:store at -20℃ for one year. avoid repeated freeze/thaw cycles. thelyophilized antibody is stable at room temperature for at least one month and for greaterthan a year when kept at -20℃. when reconstituted in sterile ph 7.4 0.01m pbs or diluentof antibody, the antibody is stable for at least six weeks at 2-4 ℃
important note: this product as supplied is intended for research use only, not for use inhuman, therapeutic or diagnostic applications.
11β-hsd2 抗体说明书
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风力发电塔筒除锈防腐技术说明
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硅晶片尺寸测量显微镜
国产两用型涂层测厚仪L180
11β-HSD2 抗体说明书
直读式混凝土含气量测定仪LC-61
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TOFD袖珍式旋入式试块ST1-45L
新农村建设生活污水处理采取什么工艺比较合适
选择金属激光切割机的注意事项，一定要看！
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电动等应变直剪仪操作步骤